High dose intravenous steroid therapy for severe posterior segment uveitis in Behçet's disease


Acar Gocgıl N.

British Journal Of Ophthalmology, cilt.86, ss.521-523, 2002 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 86 Konu: 5
  • Basım Tarihi: 2002
  • Dergi Adı: British Journal Of Ophthalmology
  • Sayfa Sayısı: ss.521-523

Özet

AIM:

To evaluate the safety and effectiveness of high dose intravenous steroid therapy (HDIST) in Behçet's disease patients with severeposterior segment uveitis attacks.

METHODS:

Five patients with ocular Behçet's disease were treated with HDIST for severe posterior segment attacks. Two patients had vasculitis, one patient had papillitis, and the other two had retinitis; four patients also had accompanying severe vitritis. The visual acuities and improvement in ocular signs after HDIST were evaluated.

RESULTS:

During HDIST, patients had no systemic complications caused by treatment. All patients responded to HDIST with evidence of a decrease in intraocular inflammatory activity and improved visual acuities within a mean time of 7 (1-15) days of commencing treatment. During follow up three out of five patients had new posterior segment attacks.

CONCLUSION:

HDIST is effective in controlling severe, vision threatening acute posterior segment Behçet's uveitis attacks and in improving visual function in a short period of time