Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging


Mauriello-Jimenez C., Henry M., Aggad D., Raehm L., Cattoen X., Man M. W. C. , ...Daha Fazla

NANOSCALE, cilt.9, ss.16622-16626, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 9 Konu: 43
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1039/c7nr04677d
  • Dergi Adı: NANOSCALE
  • Sayfa Sayıları: ss.16622-16626

Özet

Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Their endocytosis in MCF-7 cancer cells was shown with two-photon excited fluorescence (TPEF) imaging. With two-photon excited photodynamic therapy (TPE-PDT), BSPOR was more phototoxic than BSPHT, which in contrast displayed a very high signal for photoacoustic imaging in mice.