Cardiac Magnetic Resonance Postcontrast T1 Time Is Associated With Outcome in Patients With Heart Failure and Preserved Ejection Fraction

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Mascherbauer J., Marzluf B. A. , Tufaro C., Pfaffenberger S., Graf A., Wexberg P., ...More

CIRCULATION-CARDIOVASCULAR IMAGING, vol.6, no.6, pp.1056-1065, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1161/circimaging.113.000633
  • Journal Name: CIRCULATION-CARDIOVASCULAR IMAGING
  • Journal Indexes: Science Citation Index Expanded
  • Page Numbers: pp.1056-1065
  • Keywords: hypertension, pulmonary, magnetic resonance imaging, prognosis, DIFFUSE MYOCARDIAL FIBROSIS, EUROPEAN-SOCIETY, HYPERTROPHIC CARDIOMYOPATHY, PULMONARY-HYPERTENSION, SYSTOLIC FUNCTION, RISK-FACTORS, TASK-FORCE, ECHOCARDIOGRAPHY, DYSFUNCTION, COLLAGEN

Abstract

Background The underlying pathophysiology of heart failure with preserved ejection fraction (HFPEF) is incompletely understood, but myocardial extracellular matrix accumulation is thought to play a major role. Our aims were to estimate myocardial extracellular matrix using cardiac magnetic resonance T1 mapping and to assess the relationship between pathobiology/pathophysiology and prognosis.