Phenytoin toxicity with mandibular tremor secondary to intravenous administration


Türkdogan D., Onat F. , Türe U., Pamir N.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, cilt.40, sa.1, ss.18-19, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Konu: 1
  • Basım Tarihi: 2002
  • Doi Numarası: 10.5414/cpp40018
  • Dergi Adı: INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
  • Sayfa Sayıları: ss.18-19

Özet

The parenteral form or phenytoin is the most commonly used antiepileptic agent during the perioperative period in neurosurgery clinics. We report observations in a 52-year-old male patient with hypoalbumin-emia and phenytoin intoxicity following I day preoperative administration and a 7-day postoperative intravenous administration of the drug with no modification of the oral dose. This report emphasizes the need for careful surveillance of phenytoin-induced toxicity during parenteral therapy, especially in debilitated patients.