Tuberculous meningitis presenting with nonconvulsive status epilepticus

Arman F., Kaya D., Akgun Y., Kocagoz S.

EPILEPSY & BEHAVIOR, vol.20, no.1, pp.111-115, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.yebeh.2010.10.014
  • Journal Name: EPILEPSY & BEHAVIOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-115
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Nonconvulsive status epilepticus (NCSE) is an enduring epileptic condition characterized by alteration in consciousness and continuous ictal discharges on the EEG. Various etiologies have been reported. We describe the case of a 66-year-old woman with altered mental status who was diagnosed with NCSE. A workup to explain the etiology revealed tuberculous meningitis (TBM) with increased cerebrospinal fluid protein and positive tuberculous DNA polymerase chain reaction and interferon-gamma assay tests. She was treated according to the status epilepticus protocol with a four-drug anti-tuberculosis regimen to which she responded. TBM is a serious disease with insidious presentation and still constitutes a diagnostic challenge with its various presentations. Among the many presentations of tuberculosis, clinicians should consider NCSE. (C) 2010 Elsevier Inc. All rights reserved.