Association of transforming growth factor beta 1 gene polymorphism with rheumatoid arthritis in a Turkish population

Alayli G., Kara N., Tander B. , Canturk F., Gunes S., Bagci H.

JOINT BONE SPINE, vol.76, no.1, pp.20-23, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jbspin.2008.02.012
  • Title of Journal : JOINT BONE SPINE
  • Page Numbers: pp.20-23


Objective: Cytokine genes play important role, in the pathogenesis of rheumatoid arthritis (RA). In RA, the plasma and synovial fluid levels of transforming growth factor beta 1 (TGF beta 1) have been shown to be raised. The aim of this study was to investigate the relationship between the TGF beta 1 T869C polymorphism and RA in a Turkish population.