Association of transforming growth factor beta 1 gene polymorphism with rheumatoid arthritis in a Turkish population


Alayli G., Kara N., Tander B. , Canturk F., Gunes S., Bagci H.

JOINT BONE SPINE, cilt.76, ss.20-23, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 76 Konu: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jbspin.2008.02.012
  • Dergi Adı: JOINT BONE SPINE
  • Sayfa Sayıları: ss.20-23

Özet

Objective: Cytokine genes play important role, in the pathogenesis of rheumatoid arthritis (RA). In RA, the plasma and synovial fluid levels of transforming growth factor beta 1 (TGF beta 1) have been shown to be raised. The aim of this study was to investigate the relationship between the TGF beta 1 T869C polymorphism and RA in a Turkish population.