MUSCARINIC RECEPTOR SUBTYPES OF GUINEA-PIG COMMON BILE-DUCT


KARAHAN F., ALICAN I., OZKUTLU U., ONAT F. , YEGEN B., ULUSOY N., ...More

ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, vol.312, pp.140-145, 1991 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 312
  • Publication Date: 1991
  • Title of Journal : ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE
  • Page Numbers: pp.140-145

Abstract

The antagonism of carbachol-induced contractions of guinea-pig common bile duct smooth muscle strips by various antagonists has been investigated in order to find out the muscarinic receptor subtype(s) of common bile duct smooth muscle. Atropine, pirenzepine, 4-DAMP and AF-DX 116 were used as nonselective, M1-selective, M1- and M3-selective and M2-selective muscarinic antagonists, respectively.