LSIL/ASC-H (LSIL-H) in Cervicovaginal Smear: Histopathological Outcomes and Clinical Significance

Işık Kaygusuz E., Çetiner H., ŞAHİN D.

TURKISH JOURNAL OF PATHOLOGY, vol.27, no.1, pp.46-50, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.5146/tjpath.2010.01045
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.46-50
  • Keywords: Vaginal smears, Cervical intraepithelial neoplasia, SQUAMOUS INTRAEPITHELIAL LESION, ASC-H, HSIL, CATEGORY, TERMINOLOGY
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Objective: Conventional Pap smears exhibiting unequivocal features of 'low grade squamous intraepithelial lesion' (LSIL) are occasionally mixed with some cells suspicious for, but not diagnostic of 'high grade squamous intraepithelial lesion' (HSIL) on daily routine. The 2001 Bethesda System does not address the significance of such cytological entities. We have referred to these changes in our laboratory as 'LSIL, atypical squamous cells cannot exclude HSIL' (LSIL/ASC-H). In this study, we aimed to compare the cytology and biopsy results of LSIL/ ASC-H to LSIL, ASC-H and HSIL.