Journal Of Reproductive Medicine, cilt.61, ss.581-584, 2016 (SCI-Expanded)
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OBJECTIVE: To investigate the effect of azoospermia
type on fertilization and clinical pregnancy rates when
microdissection testicular sperm extraction (TESE) is
performed for sperm retrieval
in nonobstructive azoospermia
(NOA).
STUDY DESIGN: Patients
who underwent microdissection
TESE for NOA and conventional
TESE for obstructive
azoospermia (OA) were
included in the study. Intracytoplasmic
sperm injection (ICSI) results were compared
between groups.
RESULTS: The mean ages in the 2 groups were similar.
FSH and LH levels in the NOA group were significantly
higher than those of the OA group. Between groups
there was no statistically significant difference in testosterone
levels. The sperm retrieval rate was 58.56%
in NOA. Fertilization and clinical pregnancy rates were
similar for patients with NOA and OA.
CONCLUSION: In patients with NOA, microdissection
TESE accurately determines active spermatogenesis
areas via the high identification power of the operative
microscope. From these areas surgeons can collect
healthier spermatozoa, which can result in better ICSI
outcomes, the results of which are similar to those with
OA.