Does a prenatal diagnosis affect mortality and morbidity for neonatal arterial switch operation.
Cardiology in the young, cilt.32, sa.10, ss.1644-1648, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 10
- Basım Tarihi: 2022
- Doi Numarası: 10.1017/s1047951121004819
- Dergi Adı: Cardiology in the young
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Sayfa Sayıları: ss.1644-1648
- Anahtar Kelimeler: Arterial switch operation, prenatal diagnosis, transposition of great arteries, Taussig-Bing anomaly, newborn, CONGENITAL HEART-DISEASE, GREAT-ARTERIES, TRANSPOSITION, OUTCOMES
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
© The Author(s), 2022. Published by Cambridge University PressAbstract Background: The effect of prenatal diagnosis on prognosis in patients with transposition of the great arteries is not clear. In this study, we compared the outcomes after arterial switch operation. Methods: Outcome of 112 patients who had arterial switch operation in the neonatal period were analysed. The patients were divided into two groups: those who had prenatal diagnosis (Group 1; n = 34) and those who did not (Group 2; n = 78). The patients were also classified based on their diagnosis: simple transposition, transposition with ventricular septal defect and/or aortic arch hypoplasia, and Taussig–Bing anomaly. Results: In Group 1, the C-section delivery rate was higher (82% vs. 44%; p = 0.004), and it was observed that patients in Group 1 were more often intubated upon admission to the neonatal ICU (38% vs. 9%; p = 0.005). No differences were found between the two groups in terms of operation time, cardiopulmonary bypass time, post-operative invasive respiratory support duration, or extracorporeal membrane oxygenation support. It was observed that those who had Taussig–Bing anomaly had a higher mortality. Conclusions: Timely treatment have a positive effect on neonatal mortality and morbidity. That’s why all families with prenatal diagnosis of critical CHD should be recommended to have the delivery in a tertiary care hospital. Although it could not be demonstrated in this study, prenatal diagnosis has a potential to improve surgical results especially in countries or cities, which does not have enough resources for transfer and surgical units. Further efforts are needed to improve prenatal screening programmes.