GnRH agonist leuprolide acetate does not confer any protection against ovarian damage induced by chemotherapy and radiation in vitro

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Bildik G., Akin N., Senbabaoglu F., Sahin G. N., Karahuseyinoglu S., Ince Ü., ...Daha Fazla

HUMAN REPRODUCTION, cilt.30, sa.12, ss.2912-2925, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 12
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1093/humrep/dev257
  • Dergi Adı: HUMAN REPRODUCTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2912-2925
  • Anahtar Kelimeler: chemotherapy, ovarian failure, GnRH agonist, apoptosis, follicle reserve, granulosa cells, steroidogenic activity, BREAST-CANCER CHEMOTHERAPY, FERTILITY PRESERVATION, PREMENOPAUSAL WOMEN, ADJUVANT TREATMENT, HORMONE AGONISTS, GROWTH, CYCLOPHOSPHAMIDE, TRIPTORELIN, PACLITAXEL, DOCETAXEL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

STUDY QUESTION: Is there any in vitro evidence for or against ovarian protection by co-administration of a GnRH agonist with chemotherapy in human?