What Is the Optimal Treatment of Large Brain Metastases? An Argument for a Multidisciplinary Approach


Choi C. Y. H. , Chang S. D. , Gibbs I. C. , Adler J. R. , Harsh G. R. , Atalar B. , ...Daha Fazla

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.84, ss.688-693, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 84 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ijrobp.2012.01.028
  • Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
  • Sayfa Sayıları: ss.688-693

Özet

Purpose: Single-modality treatment of large brain metastases (>2 cm) with whole-brain irradiation, stereotactic radiosurgery (SRS) alone, or surgery alone is not effective, with local failure (LF) rates of 50% to 90%. Our goal was to improve local control (LC) by using multimodality therapy of surgery and adjuvant SRS targeting the resection cavity.