What Is the Optimal Treatment of Large Brain Metastases? An Argument for a Multidisciplinary Approach

Choi, Clara; Chang, Steven; Gibbs, Iris; Adler, John; Harsh, Griffith; Atalar, BANU; Lieberson, Robert; Soltys, Scott

doi:10.1016/j.ijrobp.2012.01.028

What Is the Optimal Treatment of Large Brain Metastases? An Argument for a Multidisciplinary Approach

Choi C. Y. H., Chang S. D., Gibbs I. C., Adler J. R., Harsh G. R., Atalar B., ...Daha Fazla

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.84, sa.3, ss.688-693, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 84 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.ijrobp.2012.01.028
Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.688-693
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Purpose: Single-modality treatment of large brain metastases (>2 cm) with whole-brain irradiation, stereotactic radiosurgery (SRS) alone, or surgery alone is not effective, with local failure (LF) rates of 50% to 90%. Our goal was to improve local control (LC) by using multimodality therapy of surgery and adjuvant SRS targeting the resection cavity.