The relation between p53 overexpression and lymph node metastases in clinical stage t2 and t3a transitional cell bladder carcinoma

Uygur M., Yaman I., Kutluay L., Altug U. , Erol D.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, vol.18, no.3, pp.391-395, 1999 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 3
  • Publication Date: 1999
  • Title of Journal : JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • Page Numbers: pp.391-395

Abstract

Mutant p53 protein overexpression is generally associated with poorly differentiated invasive bladder tumors. The survival in such cases is also expected to be poor. The objective of the present study was to determine whether immunohistochemical staining for p53 was predictive of lymph node metastases in early muscle invasive transitional cell bladder cancer.