Short-term Effects of Radioiodine Therapy on Auditory Function
JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY, cilt.13, sa.3, ss.322-326, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 3
- Basım Tarihi: 2017
- Doi Numarası: 10.5152/iao.2017.3264
- Dergi Adı: JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.322-326
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır
Özet
OBJECTIVE: Radioiodine therapy (RIT) is frequently utilized as an adjunctive treatment option for differentiated thyroid carcinoma following surgical intervention. The side effects of RIT are considered to emerge as a result of radioiodine accumulation in non-thyroidal tissues capable of iodine uptake. We aimed to evaluate the effects of RIT on auditory function. MATERIALS and METHODS: Patients who had undergone total thyroidectomy and diagnosed to have differentiated thyroid carcinoma were analyzed. Those who were given RIT were included. Pure-tone audiometry and distortion product otoacoustic emission (DP-OAE) results were recorded along with patient demographics, RIT dose, and thyroid hormone profiles, both before and 3 months after RIT. RESULTS: Here, 63 patients were enrolled. Following RIT, audiometric thresholds at 0.25, 0.5, 4, and 8 kHz in addition to pure-tone average increased significantly; however, the change in DP-OAE results was not statistically significant at any frequency. The RIT dose had no effect on auditory function. CONCLUSION: In this study, we found some deleterious effects of RIT on audiometric thresholds, with no significant effect on DP-OAE results.