Primary mucosal desmoplastic melanoma of the gingiva

Koseoglu R. D., Aladag I., Sezer E., Ozkan N.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.39, sa.3, ss.483-490, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3906/sag-0711-41
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.483-490
  • Anahtar Kelimeler: Desmoplastic melanoma, oral mucosa, p53, FasL, caspase-3, NEEDLE-ASPIRATION-CYTOLOGY, FAS-LIGAND EXPRESSION, MALIGNANT-MELANOMA, NEUROTROPIC MELANOMA, NECK, HEAD, APOPTOSIS, VARIANTS, ORIGIN, CELLS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Desmoplastic melanoma (DM) is a very, rare variant of malignant melanoma. Mucosal involvement in DM is exceedingly rare and the differential diagnosis is problematic for surgical pathologists. To the best Of Our knowledge only 16 cases of DM originating from mucosal surfaces of the oral cavity have been described in the literature. Herein we describe a 59-year-old male with primary DM of the oral mucosa and discuss the status of p53, caspase-3, and FasL (Fas ligand) in the pathogenesis of this rare disease.