The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model


Yavuz D., Ersoz O., Kucukkaya B., Budak Y., Ahiskali R., EKİCİOĞLU G., ...Daha Fazla

JOURNAL OF HYPERTENSION, cilt.17, sa.8, ss.1217-1223, 1999 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 8
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1097/00004872-199917080-00023
  • Dergi Adı: JOURNAL OF HYPERTENSION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1217-1223
  • Anahtar Kelimeler: albuminuria, captopril, diabetes, erythrocyte membrane charge, glomerular anionic charge, glycosaminoglycan, losartan, rat, SERUM SIALIC-ACID, CONVERTING ENZYME-INHIBITION, ANGIOTENSIN-II, SIZE-SELECTIVITY, BLOOD-PRESSURE, MICROALBUMINURIA, NEPHROPATHY, MELLITUS, ALBUMINURIA, ENALAPRIL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objective Although angiotensin-converting enzyme inhibitors are known to reduce albuminuria by preserving glomerular basement membrane anionic content, the effects of angiotensin II receptor blockage are currently not known. The aim of this study was to evaluate the effects of captopril and losartan on glomerular basement membrane anionic charges in a diabetic rat model.