Treatment results and prognostic factors in inoperable carcinoma of the cervix treated with external plus high dose brachytherapy


Garipagaoglu M., Yalvac S., Kose M. F. , Tulunay G., Kayikcioglu F., Cakmak A., ...Daha Fazla

CANCER LETTERS, cilt.136, ss.17-26, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 136 Konu: 1
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0304-3835(98)00293-6
  • Dergi Adı: CANCER LETTERS
  • Sayfa Sayıları: ss.17-26

Özet

Patients with inoperable carcinoma of the cervix treated with external plus high dose rate brachytherapy (HDRB), between 1988 and 1995 were evaluated retrospectively. According to stage, 5 year survival rates were 67.3% in stage IIb and 52.6% in stage III (P = 0001) and disease free survival (DFS) rates were 54.0% in stage IIb and 43.9% in stage III (P = 0.01), The following parameters were studied: age; stage; external beam dose; brachytherapy dose; total dose to point A; tumor mass; tumor response rate; bilateral or unilateral invasion of parametria in stage IIb; and bilateral or unilateral invasion of pelvic wall in stage mb; and the existence of hydronephrosis. The only significant parameter of 5 year survival and local control was tumor mass (P = 0.003). (C) 1999 Published by Elsevier Science Ireland Ltd, All rights reserved.