Relationship between disease severity and serum IL-6 levels in COVID-19 anosmia.

Sanli D. E. T. , Altundag A., Kandemirli S. G. , YILDIRIM D., ŞANLI A. N. , Saatci O., ...More

American journal of otolaryngology, vol.42, no.1, pp.102796, 2021 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1016/j.amjoto.2020.102796
  • Journal Name: American journal of otolaryngology
  • Journal Indexes: Science Citation Index Expanded, Scopus, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.102796
  • Keywords: COVID-19, Anosmia, IL-6, Prognosis, Mild disease, Cytokine storm, Olfactory dysfunction, Sniffin' Sticks test, Threshold discrimination identification, Computed tomography, CORONAVIRUS, INTERLEUKIN-6, INFECTION


Background: An association between IL-6 levels and cytokine storm syndrome in COVID-19 patients has been suggested. Cases with higher IL-6 levels have more rapid progression and a higher complication rate. On the other hand, COVID-19 cases with anosmia have a milder course of the disease.