The efficacy, safety and tolerability of pantoprazole-based one-week triple therapy in H-pylori eradication and duodenal ulcer healing


Sivri B., Simsek K., Hulagu S., Kadayifci A., Tozun N., AKARSU M., ...More

CURRENT MEDICAL RESEARCH AND OPINION, vol.20, no.8, pp.1301-1307, 2004 (Peer-Reviewed Journal) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 8
  • Publication Date: 2004
  • Doi Number: 10.1185/030079904125004439
  • Journal Name: CURRENT MEDICAL RESEARCH AND OPINION
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1301-1307
  • Keywords: amoxicillin, clarithromycin, duodenal ulcer, eradication, H. pylori, pantoprazole, ANTIMICROBIAL RESISTANCE, UNITED-STATES, CLARITHROMYCIN, AMOXICILLIN, METRONIDAZOLE, POPULATION, INFECTION, REGIMENS, PATTERN, TURKEY

Abstract

Objective: Recently, proton pump inhibitor (PPI)-based triple therapy has been recommended as a first line treatment in the eradication of Helicobacter pylori. The aim of this open, multicentre trial was to investigate the efficacy, safety, tolerability and the ulcer healing rate of a triple regimen consisting of pantoprazole(.) 40 mg, clarithromycin 500 mg and amoxicillin 1000 mg twice daily for 7 days, in the eradication of H. pylori in patients with duodenal ulcer in Turkey.