Performance Comparison Of 2 Different Battery Powered Mobile Antenna Analyzers And One Dedicated Mobile Open Source Qcm Platform

Kırımlı C. E., Bulut A.

2. Biyomedikal Mühendisliğinde Yenilikler Kongresi, İzmir, Turkey, 18 - 19 September 2020, pp.1-5

  • Publication Type: Conference Paper / Full Text
  • City: İzmir
  • Country: Turkey
  • Page Numbers: pp.1-5
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Abstract Quartz Crystal Microbalance (QCM) is a bulk acoustic wave piezoelectric resonator device which can be used as a mass sensitive biosensor. Resonance frequency of QCM can change due to binding of the analyte to the immobilized biorecognition element on QCM surface assuming factors such as temperature and viscosity of the medium are not changing. Monitoring of the resonance frequency can be achieved by using an impedance analyzer, especially by following phase angle peak between the series and parallel resonance frequencies close to the fundamental resonance mode. High accuracy impedance analysis usually requires bench-top cumbersome expensive devices. One inexpensive solution is using dedicated mobile instruments or antenna analyzers although the latter are designed to work at much higher frequencies, can yield reliable results. In this study, performance comparison of 2 different battery powered mobile antenna analyzers (AIM-UHF by Array Solutions and Stick 230 by RigExpert) and one dedicated mobile open source QCM (openQCM) platform was done by comparing the resonance frequency shift of a QCM resonator with a fundamental resonance frequency of 10 MHz. To do this data was collected simultaneously from the devices in changing medium viscosity environment. Glucose was spiked in distilled water in different concentrations, which were being pumped through flow cells containing QCMs using a multichannel peristaltic pump. Results were in agreement with the modified Butterworth-Van Dyke equivalent circuit of the QCM in terms of their response to changing viscosity. When combined with computational methods to increase the signal to noise ratio, antenna analyzers yield better and more accurate results when compared to mobile dedicated QCM instruments.