Vascular endothelial growth factor polymorphisms increase the risk of developing Graves' disease

Vural, Pervin; Baki, Merve; Dogru-Abbasoglu, Semra; Ozderya, Aysenur; Karadag, BERRİN; Uysal, Mujdat

doi:10.1016/j.intimp.2012.06.018

Vascular endothelial growth factor polymorphisms increase the risk of developing Graves' disease

Atıf İçin Kopyala

Vural P., Baki M., Dogru-Abbasoglu S., Ozderya A., Karadag B. , Uysal M.

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.14, ss.133-137, 2012 (SCI İndekslerine Giren Dergi)

Cilt numarası: 14 Konu: 2
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.intimp.2012.06.018
Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
Sayfa Sayıları: ss.133-137

Özet

Background: Graves' disease (GD) is a consequence of genetic and environmental factors. Vascular endothelial growth factor (VEGF) is a strong angiogenic and mitogenic factor, which plays a key role in lymphocyte infiltration, and hypervascularization in the thyroid gland of patients with GD.