Calcium Imaging of Nerve-Mast Cell Signaling in the Human Intestine.

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Buhner S., Barki N., Greiter W., Giesbertz P., Demir I., Ceyhan G., ...Daha Fazla

Frontiers in physiology, cilt.8, ss.971, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3389/fphys.2017.00971
  • Dergi Adı: Frontiers in physiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.971
  • Anahtar Kelimeler: enteric nervous system, neuropeptides, Ca2+ imaging, neuro-immune, CGRP, SP, VIP, human gut, IRRITABLE-BOWEL-SYNDROME, HUMAN SUBMUCOUS PLEXUS, IN-VITRO, SUBSTANCE-P, GUINEA-PIG, MEDIATOR RELEASE, IMMUNOGLOBULIN-E, ENTERIC NEURONS, EXCITES NEURONS, HUMAN GUT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Introduction: It is suggested that an altered microenvironment in the gut wall alters communication along amast cell nerve axis. We aimed to record for the first time signaling between mast cells and neurons in intact human submucous preparations.