A prospective, randomized, double-blind study comparing the efficacy of diltiazem, glyceryl trinitrate, and lidocaine for the treatment of anal fissure in children

Cevik, Muazez; Boleken, Mehmet; Koruk, Ibrahim; Ocal, Servet; Balcioglu, Mehmet; Aydinoglu, Asim; Karadag, Cetin

doi:10.1007/s00383-011-3048-4

A prospective, randomized, double-blind study comparing the efficacy of diltiazem, glyceryl trinitrate, and lidocaine for the treatment of anal fissure in children

Cevik M. , Boleken M. E. , Koruk I., Ocal S., Balcioglu M. E. , Aydinoglu A., ...More

PEDIATRIC SURGERY INTERNATIONAL, vol.28, no.4, pp.411-416, 2012 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 28 Issue: 4
Publication Date: 2012
Doi Number: 10.1007/s00383-011-3048-4
Title of Journal : PEDIATRIC SURGERY INTERNATIONAL
Page Numbers: pp.411-416
Keywords: Anal fissure, Children, Diltiazem, Glyceryl trinitrate, Lidocaine, CONSTIPATION, PRESSURE

Abstract

Anal fissure (AF) is a common perianal condition in children. Although adult patients with AF have been treated successfully using diltiazem, it has not been studied in children. The present randomized, prospective, double-blind study assessed the response, side effects, and recurrence of diltiazem.