JOURNAL OF PEDIATRIC RESEARCH, cilt.4, ss.63-67, 2017 (ESCI İndekslerine Giren Dergi)
Aim: Gorlin syndrome is an autosomal dominant disorder characterized by cutaneous basal cell carcinomas, odontogenic keratocysts and skeletal anomalies. Predisposition to certain types of cancers is among the main features of the disease. Chromosome instability was suspected as a mechanism for cancer predisposition. However, previous studies failed to prove the presence of chromosome instability.