European Congress of Radiology, Vienna, Austria, 3 - 07 March 2021, pp.1
The results in patients diagnosed with high-risk breast lesions with image-guided needle biopsy: a multicentre retrospective study
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AuthorsÖ. Aslan1, A. Oktay1, F. Taşkin2, N. Tunçbilek3, G. Esen2, P. Balci1, M. E. Aribal2, L. Çelik2, S. Örgüç4; 1Izmir/TR, 2Istanbul/TR, 3Edirne/TR, 4Manisa/TR
Purpose or Learning ObjectiveIn this multicenter study, the goal was to document the excisional biopsy or follow-up results of high risk lesions diagnosed on image guided CNB/VAB, and evaluate the clinical, imaging and histologic features for associated malignancy risk.
Methods or BackgroundThis is a retrospective multicentric study that include 1240 patients from 25 centers. The radiology records were searched for all image guided biopsies and pathology reports were reviewed in a 12 year period, between 2008 and 2020. Patients who had a diagnosis of high risk breast lesion on image guided core biopsy(tru-cut/vacuum biopsy) were reviewed. The patients who managed with an excisional biopsy or having at least 1 year follow-up documentation following the diagnosis of borderline lesion were included in the study. Needle biopsy type and sampling method were documented. The data were analysed using SPSS statistical program.
Results or FindingsPathological subtypes of 1240 high-risk lesions with biopsy were 28% ADH, 45% intraductal papilloma without atypia, 9.4% intraductal papilloma with atypia, 9% flat epithelial atypia, 4.5% radial scar, 4.3% Lobuler neoplasia, 0.1% pleomorphic LCIS.
ConclusionThe appropriate management after the diagnosis of a high risk lesion on image guided biopsy is controversial and recommendations between surgical excision and follow-up vary in different practices in these group of lesions.
LimitationsThe number of cases could not be increased more due to cases where follow-up results could not be achieved.
Ethics committee approvalThe institutional review board approval was obtained.
Funding for this studyNone
Area of Interest
Mammography, MR, Ultrasound
Biopsy, Vacuum assisted biopsy
Calcifications / Calculi, Cancer, Pathology