The results in patients diagnosed with high-risk breast lesions with image-guided needle biopsy: a multicentre retrospective study


Aslan Ö., Oktay Alfatlı A. N. , Taşkın F. , Tunçbilek N., Icten S. G. , Balcı P., ...More

European Congress of Radiology, Vienna, Austria, 3 - 07 March 2021, pp.1

  • Publication Type: Conference Paper / Summary Text
  • City: Vienna
  • Country: Austria
  • Page Numbers: pp.1

Abstract

Title

The results in patients diagnosed with high-risk breast lesions with image-guided needle biopsy: a multicentre retrospective study

Preferred Presentation Format

Oral Presentation

Topic

Breast

Support programme applications

none

Authors

Ö. Aslan1, A. Oktay1, F. Taşkin2, N. Tunçbilek3, G. Esen2, P. Balci1, M. E. Aribal2, L. Çelik2, S. Örgüç41Izmir/TR, 2Istanbul/TR, 3Edirne/TR, 4Manisa/TR

Body

Purpose or Learning Objective

In this multicenter study, the goal was to document the excisional biopsy or follow-up results of high risk lesions diagnosed on image guided CNB/VAB, and evaluate the clinical, imaging and histologic features for associated malignancy risk.

Methods or Background

This is a retrospective multicentric study that include 1240 patients from 25 centers. The radiology records were searched for all image guided biopsies and pathology reports were reviewed in a 12 year period, between 2008 and 2020. Patients who had a diagnosis of high risk breast lesion on image guided core biopsy(tru-cut/vacuum biopsy) were reviewed. The patients who managed with an excisional biopsy or having at least 1 year follow-up documentation following the diagnosis of borderline lesion were included in the study. Needle biopsy type and sampling method were documented. The data were analysed using SPSS statistical program.

Results or Findings

Pathological subtypes of 1240 high-risk lesions with biopsy were 28% ADH, 45% intraductal papilloma without atypia, 9.4% intraductal papilloma with atypia, 9% flat epithelial atypia, 4.5% radial scar, 4.3% Lobuler neoplasia, 0.1% pleomorphic LCIS.
In all cases, the upgrade rate to malignancy was found to be 22%. According to pathological subtypes, the upgrade rates were 40.6% in ADH, 14.8% in LN, 100% in pleomorphic LCIS, 45.7% in intraductal papilloma with atypia, 10% in intraductal papilloma without atypia, 5.4% in radial scar, and 9.3% in FEA.

Conclusion

The appropriate management after the diagnosis of a high risk lesion on image guided biopsy is controversial and recommendations between surgical excision and follow-up vary in different practices in these group of lesions.

Limitations

The number of cases could not be increased more due to cases where follow-up results could not be achieved.

Ethics committee approval

The institutional review board approval was obtained.

Funding for this study

None

Multicategories

Area of Interest

Breast

Imaging Technique

Mammography, MR, Ultrasound

Procedure

Biopsy, Vacuum assisted biopsy

Special Focus

Calcifications / Calculi, Cancer, Pathology