The effects of gingko biloba extract (EGb 761) on experimental acute pancreatitis

Zeybek N., Gorgulu S., Yagci G., Serdar M. A., Simsek A., Kaymakcioglu N., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.115, sa.2, ss.286-293, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 115 Sayı: 2
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0022-4804(03)00190-2
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.286-293
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background and objective. Acute pancreatitis is an important and fatal disease with high mortality and morbidity. Although the pathogenesis of acute pancreatitis is poorly understood, there are many studies that suggest the role for oxygen free radicals (OFRs) in the development of pancreatitis and its complications and show beneficial effects of scavenger treatment. In the present study, we aimed to investigate whether Egb761, the standardized extract of gingko biloba, restrains the generation of OFRs and ameliorates the histopathologic findings of acute pancreatitis.