The effects of gingko biloba extract (EGb 761) on experimental acute pancreatitis

Zeybek N., Gorgulu S., Yagci G., Serdar M. A., Simsek A., Kaymakcioglu N., ...More

JOURNAL OF SURGICAL RESEARCH, vol.115, no.2, pp.286-293, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1016/s0022-4804(03)00190-2
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.286-293
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background and objective. Acute pancreatitis is an important and fatal disease with high mortality and morbidity. Although the pathogenesis of acute pancreatitis is poorly understood, there are many studies that suggest the role for oxygen free radicals (OFRs) in the development of pancreatitis and its complications and show beneficial effects of scavenger treatment. In the present study, we aimed to investigate whether Egb761, the standardized extract of gingko biloba, restrains the generation of OFRs and ameliorates the histopathologic findings of acute pancreatitis.