Serum osteoprotegerin levels in patients with acute atherothrombotic stroke and lacunar infarct


Guldiken B., Guldiken S., Turgut B., Turgut N., Demir M., Celik Y., ...More

THROMBOSIS RESEARCH, vol.120, no.4, pp.511-516, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 120 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1016/j.thromres.2006.12.004
  • Journal Name: THROMBOSIS RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.511-516
  • Keywords: ischemic stroke, osteoprotegerin, atherosclerosis, small-vessel disease, large-vessel disease, lacgnar infarct, CORONARY-ARTERY-DISEASE, ISCHEMIC-STROKE, LIGAND, AGE, ATHEROSCLEROSIS, CALCIFICATION, MECHANISMS, SEVERITY, RECEPTOR, DENSITY
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background: Arterial calcification is associated with increased risk of cardiovascular events. Osteoprotegerin (OPG) is a cytokine involved in the bone metabolism and vascular calcification. Recent data support a relationship between high serum levels of OPG and increased risk for cardiovascular disease in human. The aim of this study was to evaluate the OPG serum levels in acute ischemic stroke. Our study was further designed to detect differences in serum OPG levels between subtypes of ischemic stroke.