Immune Thrombocytopenia in a Child with Neuroblastoma

İKİZOĞLU H. T., AYAN İ., TOKAT F., TECİMER T., TOPUZLU TEKANT G.

CASE REPORTS IN PEDIATRICS, cilt.2017, ss.1-4, 2017 (Hakemli Dergi) identifier identifier

  • Yayın Türü: Makale / Vaka Takdimi
  • Cilt numarası: 2017
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1155/2017/1329489
  • Dergi Adı: CASE REPORTS IN PEDIATRICS
  • Derginin Tarandığı İndeksler: Other Indexes
  • Sayfa Sayıları: ss.1-4
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Thrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tumor in children. Here we report the case of a two-year-nine-month-old patient with adrenal neuroblastoma who presented with ITP. Paraneoplastic ITP was considered in the differential diagnosis. Bone marrow infiltration and other causes of thrombocytopenia were excluded and the patient was treated with intravenous immunoglobulin and tumor resection. Platelet count increased rapidly after surgery and complete remission of ITP was achieved.