Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude

Guvenc T. S. , Huseyinoglu N. , Ozben S., Kul S., Cetin R., Ozen K., ...Daha Fazla

SLEEP AND BREATHING, cilt.20, sa.1, ss.5-13, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Konu: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s11325-015-1175-1
  • Sayfa Sayıları: ss.5-13


Purpose Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.