Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study

Akgun Z., Saglam S., YÜCEL S., Gural Z., Balik E., Cipe G., ...More

CANCER CHEMOTHERAPY AND PHARMACOLOGY, vol.74, no.4, pp.751-756, 2014 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.1007/s00280-014-2558-x
  • Journal Name: CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.751-756
  • Keywords: Chronomodulated chemotherapy, Capecitabine, Neoadjuvant chemoradiotherapy, Rectal cancer, METASTATIC COLORECTAL-CANCER, DIHYDROPYRIMIDINE DEHYDROGENASE, PREOPERATIVE RADIOTHERAPY, RADIATION-THERAPY, FOLINIC ACID, CHEMOTHERAPY, FLUOROURACIL, OXALIPLATIN, PHARMACOKINETICS, COMBINATION
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

The aim of this study was to evaluate efficacy and safety of chronomodulated capecitabine administered according to a specific time schedule (Brunch Regimen: Breakfast and Lunch) as a part of neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer.