Involvement of Insula and Cingulate Cortices in Control and Suppression of Natural Urges


Creative Commons License

Lerner A., Bagic A., Hanakawa T., Boudreau E. A., Pagan F., Mari Z., ...Daha Fazla

CEREBRAL CORTEX, cilt.19, sa.1, ss.218-223, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1093/cercor/bhn074
  • Dergi Adı: CEREBRAL CORTEX
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.218-223
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

The physiology of control and suppression of natural urges is not well understood. We used [O-15]H2O positron-emission tomography imaging to identify neural circuits involved in suppression of spontaneous blinking as a model of normal urges. Suppression of blinking was associated with prominent activation of bilateral insular-claustrum regions, right more than left; activation was also found in bilateral anterior cingulate cortex (ACC), supplementary motor areas, and the face area of the primary motor cortex bilaterally. These results suggest a central role for the insula possibly together with ACC in suppression of blinking.