Involvement of Insula and Cingulate Cortices in Control and Suppression of Natural Urges

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Lerner A., Bagic A., Hanakawa T., Boudreau E. A., Pagan F., Mari Z., ...Daha Fazla

CEREBRAL CORTEX, cilt.19, sa.1, ss.218-223, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1093/cercor/bhn074
  • Dergi Adı: CEREBRAL CORTEX
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.218-223
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

The physiology of control and suppression of natural urges is not well understood. We used [O-15]H2O positron-emission tomography imaging to identify neural circuits involved in suppression of spontaneous blinking as a model of normal urges. Suppression of blinking was associated with prominent activation of bilateral insular-claustrum regions, right more than left; activation was also found in bilateral anterior cingulate cortex (ACC), supplementary motor areas, and the face area of the primary motor cortex bilaterally. These results suggest a central role for the insula possibly together with ACC in suppression of blinking.