Vitamin D levels and parathyroid hormone variations of children living in a subtropical climate: a data mining study

Sahin O. N. , Serdar M. A. , Serteser M., Unsal I., Özpınar A.

ITALIAN JOURNAL OF PEDIATRICS, vol.44, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44
  • Publication Date: 2018
  • Doi Number: 10.1186/s13052-018-0479-8
  • Journal Indexes: Science Citation Index Expanded


Background: Vitamin D and intact parathyroid hormone (iPTH) play a crucial role in calcium homeostasis and bone health of children. Serum level of 25-hydroxyvitamin D (25-OHD) is considered to be the most accurate marker for vitamin D status. However, there have only been a few studies, with limited number of subjects, investigating the relationship between 25-OHD and parathyroid hormone (PTH) in children. The aim of this study was to evaluate the seasonal 25-OHD levels and its associations with intact parathyroid hormone (iPTH) in Turkish children at all pediatric ages; and then to define a critical decision threshold level for 25-OHD deficiency in Turkish children.