The levels of circulating markers of atherosclerosis and inflammation in subjects with different degrees of body mass index: Soluble CD40 ligand and high-sensitivity C-reactive protein

Guldiken, Sibel; Demir, Muzaffer; Arikan, ENDER; Turgut, Burhan; Azcan, Sennur; Gerenli, Murat; Tugrul, Armagan

doi:10.1016/j.thromres.2005.12.019

The levels of circulating markers of atherosclerosis and inflammation in subjects with different degrees of body mass index: Soluble CD40 ligand and high-sensitivity C-reactive protein

Atıf İçin Kopyala

Guldiken S., Demir M., Arikan E., Turgut B., Azcan S., Gerenli M., ...Daha Fazla

THROMBOSIS RESEARCH, cilt.119, sa.1, ss.79-84, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 119 Sayı: 1
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.thromres.2005.12.019
Dergi Adı: THROMBOSIS RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.79-84
Anahtar Kelimeler: obesity, atherosclerosis, inflammation, C-reactive protein, sCD40L, INSULIN-RESISTANCE, CARDIOVASCULAR RISK, OBESITY, INTERLEUKIN-6, ASSOCIATIONS, ACTIVATION, EXPRESSION, HEALTHY, DISEASE
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: It is welt demonstrated that obesity is an independent risk factor for cardiovascular diseases. Recent studies have shown that obesity, insulin resistance and atherosclerosis are closely related phenomena in which low-grade inflammatory state and prothrombotic condition has pivotal roles. It has been shown that CD40-soluble CD40 ligand (sCD40L) interactions might constitute an important mediator for vascular inflammation. The aim of the present study was to assess sCD40L in relation to hs-CRP and cardiovascular risk factors in relation to body mass index (BMI).