Is being a night owl associated with higher migraine-related disability in patients with migraine?
FRONTIERS IN NEUROLOGY, sa.17, ss.1-7, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2026
- Doi Numarası: 10.3389/fneur.2026.1812863
- Dergi Adı: FRONTIERS IN NEUROLOGY
- Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), EMBASE, Psycinfo, Directory of Open Access Journals
- Sayfa Sayıları: ss.1-7
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
Introduction: Emerging evidence suggests that circadian rhythms may influence migraine pathophysiology through interactions between sleep-wake regulation and pain modulation pathways. This study aimed to investigate the association between chronotype and migraine-related disability in patients with migraine.
Methods: In this cross-sectional observational study, 200 patients with migraine and 110 healthy controls were included. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), chronotype was evaluated using the Morningness-Eveningness Questionnaire (MEQ), and migraine-related disability was measured using the Migraine Disability Assessment Scale (MIDAS). Episodic migraine (EM) and chronic migraine (CM) subgroups were also compared.
Results: Migraine patients exhibited poorer sleep quality (PSQI: 7.28 vs. 4.37, p < 0.001), with chronic migraine (CM) patients showing the highest disability (MIDAS: 36.17 vs. 9.63, p < 0.001). No significant dierence in chronotype distribution was observed between groups (p = 0.48). Morning chronotypes had lower MIDAS scores (16.95 ± 16.17) compared to intermediate (23.93 ± 22.28) and evening types (23.55 ± 20.85), though dierences were non-significant (p = 0.082).
Discussion: While chronotype does not directly correlate with migraine-related disability, poor sleep quality in migraine patients, particularly those with CM, underscores the need for sleep-focused interventions.