Cytotoxicity of local anesthetics to rats' articular cartilage: an experimental study


Beyzadeoglu T., Torun Kose G., Ekinci I. D. , Bekler H., Yilmaz C.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.46, no.3, pp.201-207, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.3944/aott.2012.2606
  • Title of Journal : ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Page Numbers: pp.201-207
  • Keywords: Articular cartilage, bupivacaine, chondrocyte, levobupivacaine, tramadol, ARTHROSCOPIC KNEE SURGERY, INTRAARTICULAR BUPIVACAINE, RABBIT SHOULDER, IN-VITRO, ANALGESIA, MORPHINE, OSTEOARTHRITIS, CHONDROLYSIS, CHONDROCYTE, MODEL

Abstract

Objective: The aim of this study was to evaluate the effects of both in vivo and in vitro bupivacaine, levobupivacaine and tramadol on articular cartilage and chondrocytes in experimental rat models.