Cytotoxicity of local anesthetics to rats' articular cartilage: an experimental study

Beyzadeoglu T., Torun Kose G., Ekinci I. D., Bekler H., Yilmaz C.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.46, no.3, pp.201-207, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.3944/aott.2012.2606
  • Journal Name: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.201-207
  • Keywords: Articular cartilage, bupivacaine, chondrocyte, levobupivacaine, tramadol, ARTHROSCOPIC KNEE SURGERY, INTRAARTICULAR BUPIVACAINE, RABBIT SHOULDER, IN-VITRO, ANALGESIA, MORPHINE, OSTEOARTHRITIS, CHONDROLYSIS, CHONDROCYTE, MODEL
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Objective: The aim of this study was to evaluate the effects of both in vivo and in vitro bupivacaine, levobupivacaine and tramadol on articular cartilage and chondrocytes in experimental rat models.