CHA<sub>2</sub>DS<sub>2</sub>-VASc Score is a Predictor of No-Reflow in Patients With ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Intervention
ANGIOLOGY, cilt.67, sa.9, ss.840-845, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 67 Sayı: 9
- Basım Tarihi: 2016
- Doi Numarası: 10.1177/0003319715622844
- Dergi Adı: ANGIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.840-845
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır
Özet
Thrombosis and distal embolization play crucial role in the etiology of no-reflow. CHA(2)DS(2)-VASc score is used to estimate the risk of thromboembolism in patients with atrial fibrillation. We tested the hypothesis that CHA(2)DS(2)-VASc can predict no-reflow among patients who underwent primary percutaneous coronary intervention (PCI). A total number of 2375 consecutive patients with ST-segment elevation myocardial infarction were assessed for the study. Patients were divided into 2 groups as no-reflow (n = 111) and control (n = 1670) groups according to post-PCI no-reflow status. CHA(2)DS(2)-VASc scores were calculated for all patients. CHA(2)DS(2)-VASc scores were significantly higher in the no-reflow group compared to the control group. After a multivariate regression analysis, CHA(2)DS(2)-VASc score remained as an independent predictor (odds ratio: 1.58, 95% confidence interval: 1.33-1,88, P < .001) of no-reflow. Receiver-operating characteristics analysis revealed the cutoff value of CHA(2)DS(2)-VASc score 2 as a predictor of no-reflow with a sensitivity of 66% and a specificity of 59%. Moreover, in-hospital mortality was also associated with significantly higher CHA(2)DS(2)-VASc scores. In conclusion, CHA(2)DS(2)-VASc score is associated with higher risk of no-reflow and in-hospital mortality rates in patients who underwent primary PCI.