Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer


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Gure A. O. , Chua R., Williamson B., Gonen M., Ferreira C., Gnjatic S., ...More

CLINICAL CANCER RESEARCH, vol.11, no.22, pp.8055-8062, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 22
  • Publication Date: 2005
  • Doi Number: 10.1158/1078-0432.ccr-05-1203
  • Title of Journal : CLINICAL CANCER RESEARCH
  • Page Numbers: pp.8055-8062

Abstract

Purpose: Cancer-testis genes mapping to the X chromosome have common expression patterns and show similar responses to modulators of epigenetic mechanisms. We asked whether cancertestis gene expression occurred coordinately, and whether it correlated with variables of disease and clinical outcome of non-small cell lung cancer (NSCLC). Experimental