Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer

Gure A. O., Chua R., Williamson B., Gonen M., Ferreira C., Gnjatic S., ...More

CLINICAL CANCER RESEARCH, vol.11, no.22, pp.8055-8062, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 22
  • Publication Date: 2005
  • Doi Number: 10.1158/1078-0432.ccr-05-1203
  • Journal Name: CLINICAL CANCER RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.8055-8062
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Purpose: Cancer-testis genes mapping to the X chromosome have common expression patterns and show similar responses to modulators of epigenetic mechanisms. We asked whether cancertestis gene expression occurred coordinately, and whether it correlated with variables of disease and clinical outcome of non-small cell lung cancer (NSCLC). Experimental