Retinovascular findings in newborns with critical congenital heart disease: A case series

Fettah N., Kabatas E. U., Dogan V., Zenciroglu A., Dilli D., Ozyazici E., ...More

ARCHIVOS ARGENTINOS DE PEDIATRIA, vol.115, no.3, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.5546/aap.2017.eng.e175
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Critical congenital heart disease (CCHD) may cause changes in retinal vasculature. However, there is lack of data in this issue in newborns. We evaluated retinovascular changes in a series of 43 newborn with CCHD. They were divided into 2 groups according to the type of CCHD; group 1 (n=18): left obstructive CCHD and group 2 (n=25): right obstructive CCHD. Retinovascular pathologies were detected in 21 patients (48.8%); it was more frequent in group 1 (p=0.04). The most common pathology was retinal vascular tortuosity in 6 patients (33.3%) of group 1, and 4 (16.0%) in group 2. None of 21 patients with retinovascular changes required any therapy at follow-up. In multivariate analysis, only having a left obstructive CCHD was associated with the development of any retinovascular pathology (P=0.03, OR: 2.8, CI95%: 1.1-7.4). Retinovascular changes are frequent in newborn patients with CCHD.