Optimization of piribedil mucoadhesive tablets for efficient therapy of Parkinson's disease: physical characterization and ex vivo drug permeation through buccal mucosa


Celik B., Ozdemir S. , Demirkoz A. B. , Uner M.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, cilt.43, ss.1836-1845, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 43 Konu: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/03639045.2017.1349785
  • Dergi Adı: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
  • Sayfa Sayıları: ss.1836-1845

Özet

Objective: The aim of this study was optimization of buccal piribedil (PR) mucoadhesive tablets to improve its low bioavailability and provide controlled release for the treatment of Parkinson's disease.