THE EFFECT OF INTRATESTICULAR INJECTION OF AUTOLOGOUS PLATELET RICH PLASMA (PRP) ON SPERM RETRIEVAL RATES AND IVF OUTCOMES IN MEN WITH NON-OBSTRUCTIVE AZOOSPERMIA AND HISTORY OF FAILED TESTICULAR SPERM EXTRACTION


Güdelci T., Cakıroglu A. Y. , Yücetürk A., Batır Yüksel S., Karaosmanoğlu Ö., Yıldırım Köpük Ş., ...More

ASRM Scientific Congress & Expo 2021, , Maryland, United States Of America, 24 - 27 October 2021, vol.116, no.3, pp.331

  • Publication Type: Conference Paper / Summary Text
  • Volume: 116
  • City: Maryland
  • Country: United States Of America
  • Page Numbers: pp.331

Abstract

Nonobstructive azoospermia (NOA) is the absence of sperm in the ejaculate resulting from severe deficits in spermatogenesis due to primary testicular dysfunction. NOA is diagnosed in 5-10% of men undergoing infertility work-up. In order to retrieve sperm cells in men with NOA, a number of surgical techniques have been developed, including testicular sperm aspiration (TESA) and conventional or microdissection testicular sperm extraction (cTESE/mTESE). However, effective strategies to obtain spermatozoal cells in men with NOA who fail mTESE procedures are not available. The aim of the current study was to investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in men with NOA and a history of at least one previously failed mTESE procedure.