Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendritic cell generation

Hatipoglu I., Ercan D., Acilan C., Basalp A., Durali D., Baykal A. T.

IMMUNOBIOLOGY, cilt.219, ss.944-949, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 219 Konu: 12
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.imbio.2014.07.020
  • Sayfa Sayısı: ss.944-949


Hepatitis B virus (HBV) continues to be a serious worldwide health problem despite the use of protective HBV vaccines and therapeutic regimens against chronic HBV infection. Chronic HBV patients cannot induce sufficient immune responses against the virus. HBV and its antigens are believed to suppress immune responses during chronic infection. Hence, studying the role of HBV in immune suppression is very important for the development of alternative therapeutic strategies for HBV infections.