Platelet-rich plasma for enhancing surgical rotator cuff repair: evaluation and comparison of two application methods in a rat model

ERŞEN A., Demirhan M., Atalar A. C., Kapicioglu M., Baysal G.

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, vol.134, no.3, pp.405-411, 2014 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 134 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1007/s00402-013-1914-3
  • Journal Name: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.405-411
  • Keywords: Rotator cuff, Platelet-rich plasma, Rat model, RANDOMIZED CONTROLLED-TRIAL, 2-YEAR FOLLOW-UP, CRUCIATE LIGAMENT RECONSTRUCTION, GROWTH-FACTORS, CORTICOSTEROID INJECTION, LATERAL EPICONDYLITIS, STRUCTURAL INTEGRITY, HEALING ENVIRONMENT, FIBRIN MATRICES, SPORTS-MEDICINE
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Platelet-rich plasma (PRP) is a natural concentrate of autologous growth factors now being widely tested in different fields of medicine for its potential in enhancing the regeneration of tissue with low healing potential. However, studies of PRP in enhancing rotator cuff repair have been contradictory, perhaps because of how PRP is administered. The purpose of this study is to evaluate the effect of PRP and compare two different application methods of PRP on rotator cuff healing.