Low serum copeptin levels in patients with obstructive sleep apnea


Ozben S., Guvenc T. S. , Huseyinoglu N. , Sanivar H. S. , Hanikoglu F., Cort A., ...More

SLEEP AND BREATHING, vol.17, no.4, pp.1187-1192, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1007/s11325-013-0822-7
  • Title of Journal : SLEEP AND BREATHING
  • Page Numbers: pp.1187-1192

Abstract

Copeptin, the C-terminal fragment of antidiuretic hormone (ADH), is a new biomarker that has been found to be elevated in several cardiovascular disorders and is related with prognosis. Patients with obstructive sleep apnea demonstrate a tendency to develop coronary and cerebral atherosclerotic disease. Our aim was to investigate copeptin levels in untreated new diagnosed obstructive sleep apnea patients without manifest cardiovascular disorders in order to determine whether copeptin could be used as a biomarker in this group.