Perioperative outcomes following robot-assisted partial nephrectomy in elderly patients

Sharma G., Shah M., Ahluwalia P., Dasgupta P., Challacombe B. J., Bhandari M., ...Daha Fazla

WORLD JOURNAL OF UROLOGY, cilt.40, sa.11, ss.2789-2798, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 11
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1007/s00345-022-04171-4
  • Dergi Adı: WORLD JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, Gender Studies Database, MEDLINE
  • Sayfa Sayıları: ss.2789-2798
  • Anahtar Kelimeler: Robotic, Partial nephrectomy, Elderly, Propensity-matching, NEPHRON-SPARING SURGERY, RENAL-CELL CARCINOMA, RADICAL NEPHRECTOMY, OLDER PATIENTS, COMPLICATIONS, SURVIVAL, TRIFECTA, KIDNEY, MASSES, TUMORS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Objective To compare perioperative outcomes following robot-assisted partial nephrectomy (RAPN) in patients with age >= 70 years to age < 70 years. Methods Using Vattikuti Collective quality initiative (VCQI) database for RAPN we compared perioperative outcomes following RAPN between the two age groups. Primary outcome of the study was to compare trifecta outcomes between the two groups. Propensity matching using nearest neighbourhood method was performed with trifecta as primary outcome for sex, body mass index (BMI), solitary kidney, tumor size and Renal nephrometery score (RNS). Results Group A (age >= 70 years) included 461 patients whereas group B included 1932 patients. Before matching the two groups were statistically different for RNS and solitary kidney rates. After propensity matching, the two groups were comparable for baselines characteristics such as BMI, tumor size, clinical symptoms, tumor side, face of tumor, solitary kidney and tumor complexity. Among the perioperative outcome parameters there was no difference between two groups for operative time, blood loss, intraoperative transfusion, intraoperative complications, need for radical nephrectomy, positive margins and trifecta rates. Warm ischemia time was significantly longer in the younger age group (18.1 min vs. 16.3 min, p = 0.003). Perioperative complications were significantly higher in the older age group (11.8% vs. 7.7%, p = 0.041). However, there was no difference between the two groups for major complications. Conclusion RAPN in well-selected elderly patients is associated with comparable trifecta outcomes with acceptable perioperative morbidity.