IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme

Kalkan, Rasime; Atli, Emine; ÖZDEMİR, MUHSİN; Ciftci, Evrim; Aydin, Hasan; ARTAN, Sevilhan; ARSLANTAŞ, ALİ

doi:10.1016/j.gene.2014.10.027

IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme

Atıf İçin Kopyala

Kalkan R., Atli E. I. , ÖZDEMİR M., Ciftci E., Aydin H. E. , ARTAN S., ...Daha Fazla

GENE, cilt.554, sa.1, ss.81-86, 2015 (SCI İndekslerine Giren Dergi)

Cilt numarası: 554 Konu: 1
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.gene.2014.10.027
Dergi Adı: GENE
Sayfa Sayıları: ss.81-86

Özet

Purpose: To establish the frequency of IDH1 mutations and MGMT methylation in primary glioblastomas. Experimental design: We screened primary glioblastoma multiforme (GBM) in a population-based study for IDH1 mutations and MGMT methylation and correlated them with clinical data.