IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme

Kalkan, Rasime; Atli, Emine; ÖZDEMİR, MUHSİN; Ciftci, Evrim; Aydin, Hasan; ARTAN, Sevilhan; ARSLANTAŞ, ALİ

doi:10.1016/j.gene.2014.10.027

IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme

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Kalkan R., Atli E. I. , ÖZDEMİR M., Ciftci E., Aydin H. E. , ARTAN S., ...More

GENE, vol.554, no.1, pp.81-86, 2015 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 554 Issue: 1
Publication Date: 2015
Doi Number: 10.1016/j.gene.2014.10.027
Title of Journal : GENE
Page Numbers: pp.81-86

Abstract

Purpose: To establish the frequency of IDH1 mutations and MGMT methylation in primary glioblastomas. Experimental design: We screened primary glioblastoma multiforme (GBM) in a population-based study for IDH1 mutations and MGMT methylation and correlated them with clinical data.