Demodex folliculorum in renal transplant patients


Aydingoz I. E. , Mansur T., Dervent B.

DERMATOLOGY, cilt.195, ss.232-234, 1997 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 195 Konu: 3
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1159/000245949
  • Dergi Adı: DERMATOLOGY
  • Sayfa Sayıları: ss.232-234

Özet

Background: Demodex folliculorum (DF), which is a resident in human pilosebaceous follicles, has been implicated in infections of patients under cancer chemotherapy and with AIDS. Objective: We aimed to determine the influence of immunosuppression on carriage of DE Methods: Mite density was compared, of 30 renal transplant (RT) patients under a combination therapy of cyclosporine, azathioprine and prednisolone with that of age-and sex-matched controls. Two samples of standardized skin surface biopsies were taken from each subject. Results: DF was not found in any of the RT patients while a mean density of 0.55 DF/cm(2) was present in healthy subjects (Fisher's exact test, p<0.0001). The relationship between mite density and classic risk factors was not found to be statistically significant (Fisher's exact test, p>0.05). Conclusion: Our findings indicate that there may be other factors than immunosuppressive therapy influencing DF density.