The Relationship of Psoriasis and Melanocytic Nevi

CENGİZ F. P., EMİROĞLU N., BAHALI A. G., Ozkaya D., SU KÜÇÜK Ö., ONSUN N.

INDIAN JOURNAL OF DERMATOLOGY, vol.61, no.6, pp.664-667, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.4103/0019-5154.193680
  • Journal Name: INDIAN JOURNAL OF DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.664-667
  • Keywords: Melanoma, nevi, psoriasis, MALIGNANT-MELANOMA, INCIDENT CANCER, RISK, MELANOGENESIS, TOCILIZUMAB, ASSOCIATION, PROGRESSION, VITILIGO, SWEDEN, COHORT
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background: There is limited data about the relationship between psoriasis and melanocytic lesions and melanoma. Immunologic pathways which were implicated in psoriasis induce a reduction in the number of melanocytic nevi. Aims and Objectives: To investigate the number of melanocytic nevi in psoriatic patients compared with controls and its relationship with disease severity and type of treatment. Methods: We performed a prospective study in 100 psoriatic patients and 100 controls. Clinical data were recorded for all participants. Results: As compared with controls, patients had overall fewer nevi congenital nevi. Among psoriatic patients, biologic agents and disease severity did not correlate with the number of nevi. Conclusions: Psoriatic patients have fewer nevi than controls. Frequency of nevi in psoriatic patients is not related to treatment and disease severity.