The Relationship of Psoriasis and Melanocytic Nevi
INDIAN JOURNAL OF DERMATOLOGY, cilt.61, sa.6, ss.664-667, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 61 Sayı: 6
- Basım Tarihi: 2016
- Doi Numarası: 10.4103/0019-5154.193680
- Dergi Adı: INDIAN JOURNAL OF DERMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.664-667
- Anahtar Kelimeler: Melanoma, nevi, psoriasis, MALIGNANT-MELANOMA, INCIDENT CANCER, RISK, MELANOGENESIS, TOCILIZUMAB, ASSOCIATION, PROGRESSION, VITILIGO, SWEDEN, COHORT
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
Background: There is limited data about the relationship between psoriasis and melanocytic lesions and melanoma. Immunologic pathways which were implicated in psoriasis induce a reduction in the number of melanocytic nevi. Aims and Objectives: To investigate the number of melanocytic nevi in psoriatic patients compared with controls and its relationship with disease severity and type of treatment. Methods: We performed a prospective study in 100 psoriatic patients and 100 controls. Clinical data were recorded for all participants. Results: As compared with controls, patients had overall fewer nevi congenital nevi. Among psoriatic patients, biologic agents and disease severity did not correlate with the number of nevi. Conclusions: Psoriatic patients have fewer nevi than controls. Frequency of nevi in psoriatic patients is not related to treatment and disease severity.