Increased eNOS levels in hereditary angioedema

Demirturk M., Gelincik A., Cinar S., KILERCIK M., Onay-Ucar E., Colakoglu B., ...More

INTERNATIONAL IMMUNOPHARMACOLOGY, vol.20, no.1, pp.264-268, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1016/j.intimp.2014.03.007
  • Journal Name: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.264-268
  • Keywords: Hereditary angio-edema (HAE), Inflammatory cytokines, Endothelial nitric oxide synthase (eNOS), C1 inhibitor (C1-INH), NITRIC-OXIDE SYNTHASE, ENDOTHELIAL-CELLS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background: Hereditary angio-edema (HAE), characterized by recurrent episodes of angioedema involving the skin and the mucosa of the upper respiratory or the gastrointestinal tracts, results from heterozygosity for deficiency of the serine proteinase inhibitor (serpin), C1 inhibitor (C1-INH).