Toward a common interpretation of the 3Rs principles in animal research

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Lauwereyns J., Işil Ülman F. Y., Vitale A., Kostomitsopoulos N., Ahluwalia A.

LAB ANIMAL, vol.1, no.1, pp.1-4, 2024 (SCI-Expanded)

  • Publication Type: Article / Review
  • Volume: 1 Issue: 1
  • Publication Date: 2024
  • Doi Number: 10.1038/s41684-024-01476-2
  • Journal Name: LAB ANIMAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, Veterinary Science Database
  • Page Numbers: pp.1-4
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Lauwereyns, J., Bajramovic, J., Bert, B., Camenzind, S., De Kock, J., Elezović, A., Erden, S., Gonzalez-Uarquin, F., Ulman, Y. I., Hoffmann, O. I., Kitsara, M., Kostomitsopoulos, N., Neuhaus, W.,

Petit-Demouliere, B., Pollo, S., Riso, B., Schober, S., Sotiropoulos, A., Thomas, A., Vitale, A., Wilflingseder, D., & Ahluwalia, A. (2024).

Toward a common interpretation of the 3Rs principles in animal research. Lab Animal, Nov. 15. doi: 10.1038/s41684-024-01476-2. 

Abstract

Toward a common interpretation of the 3Rs principles in animal research

Many scientifc breakthroughs have depended on animal research, yet the ethical concerns surrounding the use of animals in experimentation have long prompted discussions about humane treatment and responsible scientifc practice. First articulated by Russell and Burch, the 3Rs Principles of Replacement, Reduction, and Refnement have gained widespread recognition as basic guidelines for animal research. Over time, the 3Rs have transcended the research community, infuencing policy decisions, animal welfare advocacy and public perception of animal experimentation. Despite their broad acceptance, interpretations of the 3Rs vary substantially, shaping statutory frameworks at various levels, with both technical and practical impacts.