Efficacy of Palbociclib and Endocrine Treatment in Heavily Pretreated Hormone Receptor-positive/HER2-negative Advanced Breast Cancer: Retrospective Multicenter Trial

Demir, Atakan; Mandel, Nil; PAYDAŞ, SEMRA; Demir, Gokhan; ER, ÖZLEM; Turhal, Nazim; Bavbek, Sevil; Eralp, YEŞİM; Saip, Pinar; Guler, Emine; Aydiner, Adnan; OYAN ULUÇ, BAŞAK; Kilickap, Sadettin; Uskent, Necdet; Karadurmus, Nuri; Kaplan, Mehmet; Yanmaz, Mustafa; Demir, Hacer; Alan, Ozkan; KORKMAZ, Taner; Olgun, Polat; Uysal, Ozlem; Altundag, Kadri; Gunduz, Seyda; Gunaldi, Meral; Sari, Murat; Beypinar, Ismail; BAŞARAN, Gül

doi:10.4274/balkanmedj.galenos.2020.2019.11.143

Efficacy of Palbociclib and Endocrine Treatment in Heavily Pretreated Hormone Receptor-positive/HER2-negative Advanced Breast Cancer: Retrospective Multicenter Trial

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Demir A., Mandel N. M., PAYDAŞ S., Demir G., ER O., Turhal N. S., ...More

Balkan medical journal, vol.37, no.2, pp.104-107, 2020 (SCI-Expanded)

Publication Type: Article / Article
Volume: 37 Issue: 2
Publication Date: 2020
Doi Number: 10.4274/balkanmedj.galenos.2020.2019.11.143
Journal Name: Balkan medical journal
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
Page Numbers: pp.104-107
Keywords: Breast cancer, CDK4/6 inhibitors, palbociclib, COMBINATION, RESISTANCE, LETROZOLE
Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background: The synthesis of CDK4/6 inhibitors with endocrine treatment in two series of treatment has been widely accepted as the standard for patients with estrogen receptor-positive metastatic breast cancer. In spite of this, the activity of CDK4/6 inhibitors in patients with metastatic breast cancer who have progressed despite receiving multiple lines of treatment is not well understood.